For almost two decades (1922-1941), Menahem Mendel Ussishkin headed KKL-JNF, though his work for and on behalf of the Fund went back far earlier. In 1903, Ussishkin, a Russian-born engineer and one of the leaders of the Hibbat Zion (Love of Zion) Movement, published "Our Zionist Program", a manifesto in which he suggested a plan for the settlement of Eretz Yisrael. Within a few years, he was among the founders of the workers' villages in Eretz Yisrael, including Ein Ganim, Be'er Yaakov, and Kfar Malal. For years, he championed the land as the cardinal principle and basic foundation "of all our work in Eretz Yisrael". As Fund Chairman, he paved the way to the great land purchases in the valleys: Jezreel, Zebulon, Beit She'an and Hefer. He also firmly steered the struggle against the British restrictions on land purchase.
Ussishkin was unshakable in his position on land redemption. His forcefulness won him many epithets: "The Iron Man" (the most popular one), "The Rock of Gibraltar" (coined by Henrietta Szold, the mother of Youth Aliya), "Menahem Pasha" and "Czar Menahem" (as he was called by the British Commissioner in Jerusalem. According to his biographer, Adam Ackerman, he was likened to a monotone horn with a constant refrain such as: "The redemption of the land precedes the redemption of the People"; "Jewish money can redeem the land of the Patriarchs... but only Jewish labor can make it the eternal possession of the Jewish People"; and "The solution to the Jewish question is Eretz Yisrael; the solution to the question of Eretz Yisrael is land; the solution to the land question is Keren Kayemeth LeIsrael."
The "Ussishkin Fortresses" (Kibbutz Dan and Kibbutz Dafna, established in his lifetime during the Tower-and-Stockade settlement drive), Kibbutz Kfar Menahem, and other sites were named after him.